Benzothiazoles, X
نویسندگان
چکیده
منابع مشابه
KI-catalyzed arylation of benzothiazoles from the coupling of aryl aldehydes with benzothiazoles in neat water.
A KI-catalyzed oxidative coupling of benzothiazoles with aryl aldehydes has been developed using TBHP as an oxidant in neat water under metal free conditions. Various 2-aryl benzothiazoles were prepared in 36-79% yields for 28 examples. The mechanistic studies suggested that this transformation proceeded via a radical process.
متن کاملBenzothiazoles: A New Profile of Biological Activities
Benzothiazoles are bicyclic ring system with multiple developed and examined, in vitro, their antitumor activity in applications. In the 1950s, a number of 2-aminobenzothiazoles ovarian, breast, lung, renal and colon carnicoma human cell were intensively studied as central muscle relaxants. Since lines. Pyrimido benzothiazole and benzothiazolo then medicinal chemists have not taken active inter...
متن کاملRecent advances in the chemistry and biology of benzothiazoles.
Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five-membered thiazole ring. This moiety has attracted considerable attention because of its wide range of pharmacological activities such as antitubercular, antimicrobial, antimalarial, anticonvulsant, anthelmintic, analgesic, anti-inflammatory, antidiabetic, antitumor activity, etc. In the last few years, s...
متن کاملSynthesis and 11C-Radiolabelling of 2-Carboranyl Benzothiazoles.
Dicarba-closo-dodecaboranes, commonly known as carboranes, possess unique physico-chemical properties and can be used as hydrophobic moieties during the design of new drugs or radiotracers. In this work, we report the synthesis of two analogues of 2-(4-aminophenyl)benzothiazole (a compound that was found to elicit pronounced inhibitory effects against certain breast cancer cell lines in vitro) ...
متن کاملInitial transformations in the biodegradation of benzothiazoles by Rhodococcus isolates.
Benzothiazole-2-sulfonate (BTSO3) is one of the side products occurring in 2-mercaptobenzothiazole (MBT) production wastewater. We are the first to isolate an axenic culture capable of BTSO3 degradation. The isolate was identified as a Rhodococcus erythropolis strain and also degraded 2-hydroxybenzothiazole (OBT) and benzothiazole (BT), but not MBT, which was found to inhibit the biodegradation...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1952
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.72.10_1271